The #Twitterbook by @timoreilly and @sarahm is all of the basics of twitter distilled down to a usable manual for those who may be uneasy with the technology.
It’s easy to understand, provides lots of examples, and clears up the jargon which surrounds twitter.
If you’re a late adopter, unsure of web 2.0 technology, this book is for you. However, if you are mildly conversant in social networking sites or comfortable with experimentation, bypass this book.